CHEMISTRY KNOWLEDGE
Better questions.
Better compound choices.
Practical guides to searching, selecting and sourcing research compounds. Understand the chemistry, compare the options and take the next step in the HTS collection.
Explore the practical guides.
Clear explanations, source references and useful next steps for your research workflow.
Exact, substructure or similarity search: which should you use?
Choose the right chemical search: exact structure, substructure or fingerprint similarity. Practical examples, stereochemistry checks and HTS search tips.
Read the guide Library selection02How to choose a screening compound library for your project
A practical screening-library checklist: chemical diversity, assay suitability, calculated properties, stock, quantities and documentation before purchase.
Read the guide Compound sourcing03In-stock or virtual compounds: what is the difference?
Understand available stock, virtual catalogue entries and synthesis on request. Compare the HTS libraries and prepare a clear compound sourcing enquiry.
Read the guide Building blocks04Choosing chemical building blocks for medicinal chemistry
Select chemical building blocks by structure, functional groups, protecting groups and stereochemistry. Prepare a precise HTS sourcing or synthesis enquiry.
Read the guide Medicinal chemistry05Fluorinated heterocycles: how to compare research compounds
Understand what fluorination can change, why position matters and how to shortlist fluorinated heterocycles without assuming improved potency or properties.
Read the guide Medicinal chemistry06Spirocyclic building blocks: shape, substitution and sourcing
What makes a compound spirocyclic? Compare ring sizes, heteroatoms, substitution vectors and practical sourcing requirements in medicinal chemistry research.
Read the guide PROTAC chemistry07PROTAC building blocks: what to specify before ordering
A practical PROTAC sourcing guide: distinguish complete degraders from building blocks and specify attachment points, linker features and chemical requirements.
Read the guide Data & workflow08SMILES, SDF and chemical databases: a practical customer guide
Understand structure strings, SDF files and SQLite catalogue downloads. Preserve chemical identity, manage compound IDs and prepare reliable bulk searches.
Read the guidePUT THE GUIDES INTO PRACTICE
Explore chemistry for your project.
Search structures, compare stock and virtual entries, or discuss a tailored selection and larger quantities.
Published by HTS Biochemie-Innovationen GmbH. Guides distinguish general chemistry from catalogue information. Sources are linked where scientific or technical concepts are discussed. Questions or corrections? Contact the team.